Hydrafinil (9-Fluorenol) review | Everything that you should know | 2020

This is a complete guide and review of Hydrafinil, also known as 9-Fluorenol or just Fluorenol. A lot of users love it because of how similar to Modafinil this nootropic is. Some users actually get identical effects from these two. The great this about 9-Fluorenol is that it’s very affordable, unlike Modafinil.

Let’s get started.

Hydrafinil (9 Fluorenol) review

In this guide / review, you will find out everything you need to know about Hydrafinil, including:

  • What is Hydrafinil
  • Mechanism of action
  • Is Hydrafinil legal in my country
  • Where to buy high-quality, pure Hydrafinil
  • What are the benefits and side effects of taking this nootropic

We will answer all of these questions as well as go over other Hydrafinil topics such as the half-life, dosages, safety profile and more.

Before we begin, we need to ehmphasize a clear disclaimer. The information depicted in this article is purely for informational purposes only. You should consult your physician about medications and nutritional supplements. Please contact your healthcare professional before making any changes to your lifestyle.

With that being said, let’s dive right in by first explaining what Hydrafinil actually is.

What is Hydrafinil

Hydrafinil, also known as 9-Fluorenol or just Fluorenol, is a metabolite of Modafinil. It’s categorized under eugeroics (wakefulness-promoting agents).

Because it has positive effects on our mental skills / cognition, it also falls under the category of nootropics.

More specifically, 9-Fluorenol is a nootropic that is known to be very similar to Modafinil. The difference between them is the mechanism of action and strength.

Hydrafinil is actually 39% stronger as an eugeroic than Modafinil – 39% more wakefulness enhancing. It also has milder effects on dopamine and a milder crash.

A big reason for its rising popularity is also the affordability, it’s a lot cheaper than most other eugeroics. It’s presently being sold as an unregulated compound online under the brand name “Hydrafinil”.

Some Hydrafinil facts:

  • It’s not a stimulant.
  • Even though the Modafinil effects are similar to some stimulants, it’s actually a eugeroic – wakefulness promoting agent.
  • It won’t make you speedy and it doesn’t have a crash like a lot of similar compounds do.
    Hydrafinil is not addictive. In fact, some users report that Fluorenol helped them get over addictions.
  • It works, really, really well.

Is Hydrafinil legal

Hydrafinil is an unregulated compound. Obviously, because of that you can legally buy and use it in every country in the world. Anybody can buy and use this nootropic.

It’s legal in every country in the world as of 2020. Unlike its “brother” Modafinil, 9-Fluorenol isn’t a regulated, FDA approved compound, at least not yet.

In short, anybody can legally buy and use Fluorenol in every country in the world.

How does Hydrafinil work

According to research and scientists, Hydrafinil mainly works as a (DRI) reuptake inhibitor and a 5-HT6 receptor antagonist.

The Hydrafinil mechanisms of action are:

  • Dopamine reuptake inhibitor – As a DRI, Fluorenol increases dopamine concentrations. Increased dopamine concentrations are proven to enhance cognition.
  • 5-HT6 receptor antagonist – Antagonism of the 5-HT6 receptor causes an increased production of choline as well as an increase in dopamine concentrations. Increased dopamine concentrations and choline levels improve cognition and performance
  • Increasing Histamine levels – Hydrafinil enhances histamine levels in the hypothalamus. Histamine plays a major role in regulating sleep cycles.
  • Increasing Glutamane levels – As a 5-HT6 receptor antagonist, Hydrafinil causes an increase in the production of glutamane in the brain. This results in enhanced memory and learning capabilities.
  • Increasing Norepinephrine levels – According to the Hydrafinil suppliers, Fluorenol increase norepinephrine levels by antagonizing the 5-HT6 receptors. Increased levels of norepinephire can lead to improved cognition. However, there isn’t a lot of research that supports this mechanism of action.


The benefits of Hydrafinil are:

But how do these Fluorenol benefits actually happen? Let’s cover that.

Improved mood, cognition and memory

As we said, Hydrafinil works mainly as a 5HT6 receptor antagonist.

Its improved mood, cognition and memory benefits come from the antagonism of the 5HT6 receptor. This is because it results in  increased choline levels, dopamine concentrations as well as increased levels of norepinephrine. All of these have been proven to have very positive effects on cognition, mood and memory.

Wakefulness, alertness

Hydrafinil has wakefulness and alertness effects, as do the other eugeroics such as Modafinil, Adrafinil, Flmodafinil…

Eugeroics are also called wakefulness-promoting agents that are meant to have wakefulness and alertness effects.

Most eugeroics, including Hydrafinil and Modafinil, achieve this as a DRI (dopamine reuptake inhibitor).

Here is how a Hydrafinil user describes its wakefulness effect:

“It’s wakefulness enhancement is more for getting up early in the morning, not for pulling off all nighters.”

Side effects

Reports have shown that Hydrafinil has fewer and milder side effects compared to Modafinil.

Even though Hydrafinil side effects are rare and most people don’t even notice them, there are still some side effects that some people might experience at higher dosages:

  • An increase or a decrease in hunger – This can hardly be called a side effect but it’s still something that a few users reported
  • Nausea
  • Headaches

It’s worth noting, however, that Fluorenol has not gone through any human trials yet. Because of this, there aren’t any yet that research the Hydrafinil side effects in humans. All that we have so far, are the studies done in rodents and primates.

Hydrafinil could cause some side effects that we just aren’t aware of yet because we haven’t done human trials.

To summarize, Fluorenol could be safe. Users report that it’s safe but that hardly evidence. Some other eugeroics, however, like Modafinil and Armodafinil have been proven to be completely safe. They also have a long track record of studies backing them up. Hydrafinil is quite similar to these two but when it comes to its safety profile, only the future studies will be able to tell that with 100% certainty

Hydrafinil Vs other Eurogics

How does Fluorenol compare to some other popular eurogics such as Modafinil, Adrafinil, Flmodafinil, Fluoromodafinil, etc.?

Let’s find out.

Hydrafinil Vs Modafinil

Modafinil is the most popular eugeroic. It’s also been proven to be safe and is backed by tons of research and human trials. The bad thing about it, however, is that it’s very expensive. Hydrafinil is very similar to Modafinil with the exception of being expensive.

Because Modafinil is the most popular eugeroic, a lot of Fluorenol users have this question: How do they compare?

Hydrafinil is actually 39% stronger as an eugeroic than Modafinil – 39% more wakefulness enhancing. It also has milder effects on dopamine and a milder crash. 

Modafinil, however, has a stronger dopamine reuptake inhibitor effect. This means that it blocks the effects of stimulants.

In my opinion, Hydrafinil seems like a great eugeroic but the biggest problem with it is that it’s just not that well researched yet. Modafinil, on the other hand, is backed with a lot of research and human trials.

Hydrafinil Vs Adrafinil

These two are often compared, mainly because they both cost roughly the same.

Users suggest that Fluorenol is slightly more potent than Adrafinil, other than that, however, they are very similar when it comes to their effects.

It’s worth noting, however, that Adrafinil has a lot more research backing it. Because of this, it has a much better safety profile. 

Adrafinil has been voluntarily discontinued in September of 2011. Probably the main reason for the discontinuation was Modafinil which is essentially a better developed Adrafinil.

Hydrafinil Vs Fluoromodafinil

Fluoromodafinil has higher DRI (dopamine reuptake inhibitor) effects. This means that it can block the effectts of some stimulants.

It has very similar wakefulness and alertness effects to Hydrafinil and they are roughly equal in strength.

The main differences, however, are that Fluoromodafinil doesn’t have 5HT6 effects and that it has a much longer half-life than Hydrafinil. Fluoromodafinil has a 9-12 hour half-life which is about twice the amount of Fluorenol.


Contrary to Modafinil and some other eugeroics (wakefulness-promoting agents), Hydrafinil has a quite short half-life of 7 hours.

This essentially means the benefits are only going to last about 7 hours and not throughout the whole day. Users who want it to last throughout the whole day need to take two dosages of Hydrafinil per day, the first in the morning and the second in the afternoon.

When it comes to the half-life of nootropics, 9-Fluorenol is right in the middle. Some nootropics such as GTS-21 have 2-3 hour half-lives and others such as 9-Me-BC or IDRA-21 have half-lives of over 24 hours.


Starting at small dosages is always a good idea with almost all compounds. Some people might disagree and mention attack dosages, but that’s a different topic.

The recommended Hydrafinil dosage and what most users take is 50mg. Obviously, you can take it up to three times per day because of the half-life. So esentially, you can take up to 150mg of Fluorenol a day split into two or three parts.

Where to buy Hydrafinil

There are a lot of places where you can buy this nootropic, but I recommend that you get it from science.bio.

Science.bio sells great, high-quality and most importantly pure products which are all 3d party tested.

You can use the code sarmguide10 to get 10% off on your order. This seems to be the biggest discount code as of May 2020.


In conclusion, Hydrafinil is a great nootropic and eugeroic. It’s very similar to Modafinil with basically identical benefits and it’s a lot more affordable.

The bad thing about Hydrafinil, however, is that there aren’t that many human trials done. Some users don’t like it because of the short half-life (7 hours). Its half-life means that you have to take Hydrafinil two times a day in order to have it last throughout the whole day.

Other than that, however, it’s a great nootropic.

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