Ecdysterone Review, Benefits, Dosage, Side Effects | November 2021

Many neurohackers are realizing that optimal brain function depends on a lot more than just focusing on neurotransmitters and hormones in the brain.

The role of exercise and bodybuilding on our mind is pivotal and therefore, an unavoidable part of brain optimization.

Ecdysterone Review

Enter Ecdysterone, a natural compound which not only has some nootropic effects but also helps out during exercise.

This Ecdysterone review will show you:

  • How Ecdysterone works
  • Ecdysterone benefits in the body and brain
  • The optimal dosage for best results
  • Side effects you can expect

Where to buy the best Ecdysterone analogue

What is Ecdysterone

Ecdysterone belongs to a class of natural anabolic steroids called ecdysteroids, which are obtained from insects and some plants.

Ecdysterone, along with Turkesterone is one of the most popular forms of ecdysteroids and has shown high anabolic activity.

Ecdysterone is also known as 20-Hydroxyecdysone and Beta Ecdysterone, the latter of which is the most potent form of this compound.

To understand the potency and potential of ecdysterone, let’s just consider that scientists who are actively researching this compound are calling for a ban of ecdysterone in competitive sports!

How Does It Work

The main function of Ecdysterone is modulating selective estrogen receptor-β.

Many people become worried about estrogenic side effects at the mention of an estrogen receptor but those worries are unwarranted, since only estrogen receptor alpha carries these adverse effects.

Also, Ecdysterone doesn’t affect the HPT axis, which means that you won’t need to cycle this compound or be worried about androgenic side effects.

Moving on, Ecdysterone also affects protein synthesis through the MAS1 receptor, which is known to be connected with energy output and muscle increase.

Lastly, Ecdysterone increases some GPCR proteins, which are once again involved with protein synthesis.

Is Ecdysterone Legal

Yes, Ecdysterone is legal to buy in every country of the world, including Australia.

While Ecdysterone is not FDA approved, it shows potent anabolic effects on human subjects and is currently on the WADA monitoring program.

Lack of human studies is probably the only reason why this compound is not completely banned yet but that might very well change in the near-future.

Ecdysterone Benefits

1. Increases IGF-1 Growth Hormone

Not just one but several celular studies have shown that Ecdysterone increases IGF-1, which is a very important growth hormone.

This study has not yet been replicated in humans but judging from anecdotal reports which cite anti-aging, brain health and antioxidant benefits, we can safely assume it does have an effect on IGF-1.

2. Increases Muscle Mass

Studies on mice reveal that Ecdysterone affects estrogen receptor Beta, which is known to have anabolic properties including increased muscle mass and better muscle cell regeneration.

Not just that but a ten-week human study looked at placebo, 200mg and 800mg supplementation of Ecdysterone.

The 800mg group increased muscle mass by seven pounds while the placebo group numbers remained unchanged.

The scientists deemed the experiment a success and called for the inclusion of Ecdysterone into the WADA banlist.

3. Has Adaptogenic Effects

Adaptogens promote homeostasis in the body and most importantly, rid the body of stress.

Stress is so perilous on the brain that it not only shrinks but also kills neurons, according to a recent report.

Given how hectic our modern lifestyles are, this effect of Ecdysterone is one of the most welcomed ones.

4. Preserves Muscle Mass

When Ecdysterone was given to pigs, it successfully helped them retain and preserve muscle mass.

While this effect hasn’t been tested on humans, it should work, as pigs and humans share many similarities, with pig heart valves already being used in humans.

5. Improves Sleep Quality

Ecdysterone has been described as having a hypnotic effect in a study done on mice. It improved sleep without impairing motor function.

The researchers also looked into potential anxiolytic effects of Ecdysterone but found none, at least not in mice.

Ecdysterone Dosage And Cycle

Although there have been quite a few tests performed on humans, a recommended dosage has yet to be found.

Scientists used up to 800mgs per day in their research and Ecdysterone did show a dose-dependent effect.

When accounting for all the research data and anecdotal reports, we found 200mgs of Ecdysterone per day to yield the best results.

Not only will you avoid most side effects with such a dosage, you’ll also take enough to notice the difference in your body and mind.

Taking Ecdysterone just once per day is enough and the best time to take it is an hour before going to the gym.

You don’t necessarily have to cycle Ecdysterone but if you want to stay in tune with the latest science, you should take it for ten weeks and then have some time off.

Ecdysterone Side Effects

At worst, the dosage we recommend could cause headaches, nausea and an upset stomach.

However, you will not experience any other side effects and most importantly, the adverse effects mentioned above will disappear within the first two weeks.

All in all, Ecdysterone is quite safe to use and you shouldn’t really have any problems with it.

Also important to mention is that you won’t have to do bloodwork, a hepatic panel or PCT after your cycle, since Ecdysterone is not androgenic and doesn’t worsen your biomarkers.

Ecdysterone VS Turkesterone

Although these two compounds are very similar and sometimes used synonymously in literature, they are not one and the same.

In fact, Turkesterone is a bit more potent when compared to Ecdysterone (around 12% more weight gain in rats per day with Turkesterone).

That is the only thing Turkesterone has going for it, because it’s WAY more expensive, with monthly dosages costing up to 120$.

Not only that but Turkesterone also has problems with bioavailability; only complexed Testosterone stands a chance but even then, you’re imbuing 500mgs of product for 50mgs of Turkesterone.

That is simply uneconomical and that’s why we’re recommending Beta Ecdysterone to our readers.

Where to Buy Ecdysterone

You have to be very careful when buying Ecdysterone, since research confirms that many vendors who peddle ecdysterone supplements actually sell underdosed products.

In one instance, the product contained 97% less Ecdysterone than was advertised!

For that reason, we only recommend companies that we’ve personally tested and vetted.

If you want pure Beta Ecdysterone, check out our recommended list of companies. Not only is this list an exhaustive account of the best companies in the game, it also gives you the most economical options.


Ecdysterone exerts many nootropic effects through IGF-1 modulation and many anabolic effects through estrogen receptor beta activation.

This makes it a multi-purpose compound and helps keep the adage ‘a healthy mind in a healthy body’ alive.

To conclude this Ecdysterone review, this is a very potent supplement with almost zero side effects.

Surely something you would want to get your hands on!

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